Table 9 Diagnostic value of laboratory tests for the diagnosis of pneumonia

From: Diagnostic value of signs, symptoms and diagnostic tests for diagnosing pneumonia in ambulant children in developed countries: a systematic review

Pneumonia prevalence (5) Nijman et al.39 (13) Irwin et al.40 (6.1) Oostenbrink et al.35 (6.2) Oostenbrink et al.35 (6.3) Oostenbrink et al.35 (10) Urbankowska et al.31
6.7% 11.4% 16% 14% 7% 72%
  Present vs absent Present vs absent Present vs absent Present vs absent Present vs absent Present vs absent
Mean CRP (mg/L) 47.5 vs 12.4      
Median CRP (mg/L)   49.0 vs 14.3a 86 vs 22a 109 vs 31a 61 vs 31a 1.95 vs 4.7a
Mean WBC (×109/L)    17.4 vs 12.8a 18.1 vs 12.7a 17.0 vs 19.1  
Median WBC (×109/L)   11.8 vs 10.8a     
Median WBC count (cells/μL)       10.1 vs 11.3
Median lymphocyte count (cells/μL)       3.6 vs 1.9a
Median neutrophil count (×109/L)   8.0 vs 6.2a     
Median neutrophil count (cells/μL)       4.3 vs 7.9a
NGAL (ng/L)   92.1 vs 69.7a     
PCT (µg/L)   0.49 vs 0.18a     
Resistin (ng/L)   67.3 vs 35.7a     
  1. CRP C-reactive protein, WBC white blood cell count, NGAL neutrophil gelatinase-associated lipocalin, PCT procalcitonin
  2. aStatistically significant difference