Fig. 2: Polymorphic SVAs were associated with markers of PD progression in the PPMI cohort. | npj Parkinson's Disease

Fig. 2: Polymorphic SVAs were associated with markers of PD progression in the PPMI cohort.

From: Reference SVA insertion polymorphisms are associated with Parkinson’s Disease progression and differential gene expression

Fig. 2

a PD individuals with the AA genotype of SVA_67 had a significantly higher ipsilateral caudate/putamen CDR at both 12 and 24 months compared to those with PA and PP genotypes. b PD individuals with the AA genotype of SVA_11 had a significantly higher MDS-UPDRS part II score at 36 months compared to those with PA and PP genotypes. c PD individuals with the PA genotype of SVA_24 had a significantly higher Hoehn and Yahr score at 36 months compared to those with AA and PP genotypes. 95% confidence intervals are represented by the blue bar. *p < 0.05, **p < 0.01 and ***p < 0.001 (Tukey adjusted p values are reported).

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