Fig. 3 | npj Aging and Mechanisms of Disease

Fig. 3

From: The annual rate of coronary artery calcification with combination therapy with a PCSK9 inhibitor and a statin is lower than that with statin monotherapy

Fig. 3

a,b: Comparison of annual percentage change in coronary artery calcium score (CAC) between no-statin-no-PCSK9 inhibitor therapy (n = 10), statin monotherapy (n = 15), and add-on PCSK9 inhibitor therapy in the paired longitudinal study (n = 16). Data were expressed as the median and 10th–90th percentiles. The horizontal line inside the box is the median. Boxes represent the interquartile range (25th–75th percentile). Whiskers represent the 10th–90th percentile. The x marks in the box indicate the average. a linearized CAC score progression, b log-transformed CAC score progression. *P < 0.05 vs. no-statin-no-PCSK9 inhibitor therapy and **P < 0.05 vs. statin monotherapy by the non-parametric Mann–Whitney U-test

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