To overcome key challenges in scaffolding chromosome-level haplotypes with Hi-C data, we developed HapHiC, a Hi-C scaffolding tool that exhibits superior performance in handling haplotype-resolved assemblies without the need for reference genomes. We used HapHiC to construct the complex genome of triploid Miscanthus × giganteus.
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References
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This is a summary of: Zeng, X. et al. Chromosome-level scaffolding of haplotype-resolved assemblies using Hi-C data without reference genomes. Nat. Plants https://doi.org/10.1038/s41477-024-01755-3 (2024).
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Achieving de novo scaffolding of chromosome-level haplotypes using Hi-C data. Nat. Plants 10, 1157–1158 (2024). https://doi.org/10.1038/s41477-024-01756-2
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DOI: https://doi.org/10.1038/s41477-024-01756-2
