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Genome maintenance

A light switch for DNA break repair

Organisms have developed specialized and intricate mechanisms to cope with environmental threats that depend on their natural habitat and ability to move. Arabidopsis demonstrates an impressive adaptation using cryptochrome 1 to maintain genomic stability through a blue-light-mediated process that involves the recruitment of repair proteins to double-strand breaks.

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Fig. 1: Double-strand break repair via SMC5/6 depends on activated CRY.


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Correspondence to Marcel Tijsterman.

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Kralemann, L.E.M., Tijsterman, M. A light switch for DNA break repair. Nat. Plants 9, 1178–1179 (2023).

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