Intracellular H2O2 has emerged as a central player in signalling and stress acclimation, but how specificity is achieved remains elusive. Cytosolic peroxiredoxins play a decisive role as they sense H2O2 and transmit the oxidation signal through the formation of disulfide bridges, leading to stomatal closure that reduces pathogen entry.
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The authors declare no competing interests.
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Dietz, KJ., Vogelsang, L. H2O2 sensing in immunity. Nat. Plants 8, 1140–1141 (2022). https://doi.org/10.1038/s41477-022-01256-1
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