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ROS signalling

H2O2 sensing in immunity

Intracellular H2O2 has emerged as a central player in signalling and stress acclimation, but how specificity is achieved remains elusive. Cytosolic peroxiredoxins play a decisive role as they sense H2O2 and transmit the oxidation signal through the formation of disulfide bridges, leading to stomatal closure that reduces pathogen entry.

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Fig. 1: The thiol peroxidase PRXII functions as regulator of OST1-dependent stomatal closure.


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Correspondence to Karl-Josef Dietz.

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Dietz, KJ., Vogelsang, L. H2O2 sensing in immunity. Nat. Plants 8, 1140–1141 (2022).

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