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A mechanism regulating centromere distribution in Arabidopsis thaliana

The biological importance of centromere distribution in the nucleus, which is classified as polarized or dispersed, has been debated. Molecular and cytogenic analyses have revealed that two regulatory processes establish a dispersed distribution and that centromere distribution might be linked to the maintenance of genome integrity.

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Fig. 1: Regulation of centromere distribution by CII and nuclear envelope proteins.


  1. Ono, T. et al. Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. Cell 115, 109–121 (2003). This paper reports the function of condensin II in chromosome condensation.

    Article  CAS  Google Scholar 

  2. Hoencamp, C. et al. 3D genomics across the tree of life reveals condensin II as a determinant of architecture type. Science 372, 984–989 (2021). This paper reports the function of condensin II in determining 3D chromatin architecture.

    Article  CAS  Google Scholar 

  3. Sakamoto, Y. et al. Subnuclear gene positioning through lamina association affects copper tolerance. Nat. Commun. 11, 5914 (2020). This paper reports the subnuclear localization of a plant lamina protein, CROWDED NUCLEI, and its function in gene positioning.

    Article  CAS  Google Scholar 

  4. Grob, S. et al. Hi-C analysis in Arabidopsis identifies the KNOT, a structure with similarities to the flamenco locus of Drosophila. Mol. Cell 55, 678–693 (2014). This paper reports the 3D architecture of the plant genome, achieved using Hi-C analysis.

    Article  CAS  Google Scholar 

  5. Shao et al. Creating a functional single-chromosome yeast. Nature 560, 331–335 (2018). This paper reports the biological characterization of Saccharomyces cerevisiae harbouring a single chromosome.

    Article  CAS  Google Scholar 

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This is a summary of: Sakamoto, T. et al. Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins. Nat. Plants (2022).

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A mechanism regulating centromere distribution in Arabidopsis thaliana. Nat. Plants 8, 877–878 (2022).

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