The biological importance of centromere distribution in the nucleus, which is classified as polarized or dispersed, has been debated. Molecular and cytogenic analyses have revealed that two regulatory processes establish a dispersed distribution and that centromere distribution might be linked to the maintenance of genome integrity.
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References
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This is a summary of: Sakamoto, T. et al. Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins. Nat. Plants https://doi.org/10.1038/s41477-022-01200-3 (2022).
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A mechanism regulating centromere distribution in Arabidopsis thaliana. Nat. Plants 8, 877–878 (2022). https://doi.org/10.1038/s41477-022-01204-z
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DOI: https://doi.org/10.1038/s41477-022-01204-z