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Shutting the door on polysaccharide methylation

Methylation is a frequent modification of glycans and polysaccharides. This process relies on the transport of cytosolic S-adenosyl-l-methionine (SAM) into the Golgi lumen. This work identifies Golgi-localized major facilitator superfamily transporter members as putative SAM transporters in plants and reveals their importance for polysaccharide methylation and maintenance of the properties of cell walls.

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Fig. 1: Discovery of Golgi SAM transporters reveals the importance of polysaccharide methylation.


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This is a summary of: Temple, H. et al. Golgi-localized putative S-adenosyl methionine transporters required for plant cell wall polysaccharide methylation. Nat. Plants (2022).

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Shutting the door on polysaccharide methylation. Nat. Plants 8, 609–610 (2022).

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