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A structural view of salicylic acid perception

Salicylic acid (SA) is an essential hormone for plant immune responses. In Arabidopsis, SA is perceived by two groups of receptors, NPR1 and NPR3/4, which play opposite roles in regulating defence gene expression. How SA binds to its receptors is now revealed by crystal structure analysis.

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Fig. 1: A model for SA perception.


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We thank N. Zheng for discussions, K. Ao for careful reading of the manuscript and K. T. Devendrakumar for assistance with making the figure.

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Correspondence to Yuelin Zhang.

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Li, X., Zhang, Y. A structural view of salicylic acid perception. Nat. Plants 6, 1197–1198 (2020).

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