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Editing through infection

A negative-strand RNA virus is engineered to express both CRISPR-associated protein 9 (Cas9) and single-guide RNAs, enabling gene editing as the virus infects the plant.

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Fig. 1


  1. 1.

    Altpeter, F. et al. Plant Cell 28, 1510–1520 (2016).

    CAS  PubMed  PubMed Central  Google Scholar 

  2. 2.

    Ma, X., Zhang, X., Liu, H. & Li, Z. Nat. Plants (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  3. 3.

    Cody, W. B. & Scholthof, H. B. Annu. Rev. Phytopathol. 57, 211–230 (2019).

    CAS  Article  Google Scholar 

  4. 4.

    Honig, A. et al. Mol. Plant 8, 1292–1294 (2015).

    CAS  Article  Google Scholar 

  5. 5.

    Marton, I. et al. Plant Physiol. 154, 1079–1087 (2010).

    CAS  Article  Google Scholar 

  6. 6.

    Ali, Z. et al. Mol. Plant 8, 1288–1291 (2015).

    CAS  Article  Google Scholar 

  7. 7.

    Ali, Z., Eid, A., Ali, S. & Mahfouz, M. Virus Res. 244, 333–337 (2018).

    CAS  Article  Google Scholar 

  8. 8.

    Mei, Y. et al. Plant Direct 3, e00181 (2019).

    Article  Google Scholar 

  9. 9.

    Hu, J. et al. Mol. Plant Pathol. 20, 1463–1474 (2019).

    CAS  Article  Google Scholar 

  10. 10.

    Yin, K. et al. Sci. Rep. 5, 14926 (2015).

    CAS  Article  Google Scholar 

  11. 11.

    Ellison, E. E. et al. Nat. Plants 6, 620–624 (2020).

    CAS  Article  Google Scholar 

  12. 12.

    An, H., Kim, G., Wu, K. & Kang, C. Virus Res. 171, 168–177 (2013).

    CAS  Article  Google Scholar 

  13. 13.

    Wang, Q. et al. PLoS Pathog. 11, e1005223 (2015).

    Article  Google Scholar 

Download references

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Correspondence to Daniel F. Voytas.

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The authors declare no competing interests.

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Dinesh-Kumar, S.P., Voytas, D.F. Editing through infection. Nat. Plants 6, 738–739 (2020).

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