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FUNCTIONAL METABOLOMICS

Tomato multiomics at aPEELing resolution

Nature Plants volume 6, pages 1394–1395 (2020)Cite this article

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An Author Correction to this article was published on 01 December 2020

This article has been updated

The peel of fruits represents a major defensive barrier. A new study analysing comprehensive transcript and metabolite data from tomato skin provides mapping of the genomic regions allowing for the coordinated regulation of metabolism, development and fungal defence at an exquisite resolution.

In order to understand the cellular transcript–metabolite networks of the tomato peel and their interaction(s) with pathogen response, Szymański and colleagues profiled 580 lines representing backcross inbred- and introgression-line populations of S. pennellii. They achieved this via transcriptome analysis of peels at the breaker stage and liquid chromatography mass spectrometry-based metabolomics analysis of peels at the breaker and red ripe stages, alongside assays with the necrotrophic fungal pathogen Botrytis cinerea at the latter ripening stage. As a result, they were able to identify hundreds of expression quantitative trait loci (eQTL) and metabolite QTL (mQTL), as well as genes and metabolites associated with enhanced resistance to the generalist pathogen.

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Fig. 1: General overview of the pipeline and data collection.

Change history

  • 01 December 2020

    A Correction to this paper has been published: https://doi.org/10.1038/s41477-020-00825-6.

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Authors and Affiliations

  1. Max-Planck-Institute of Molecular Plant Physiology, Potsdam-Golm, Germany

    Alisdair R. Fernie & Saleh Alseekh

  2. Center of Plant Systems Biology and Biotechnology, Plovdiv, Bulgaria

    Alisdair R. Fernie & Saleh Alseekh

Authors
  1. Alisdair R. Fernie
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  2. Saleh Alseekh
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S.A. prepared materials and create the figure, and A.R.F. wrote the manuscript.

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Correspondence to Alisdair R. Fernie.

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The authors declare no competing interests.

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Fernie, A.R., Alseekh, S. Tomato multiomics at aPEELing resolution. Nat. Plants 6, 1394–1395 (2020). https://doi.org/10.1038/s41477-020-00807-8

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  • DOI: https://doi.org/10.1038/s41477-020-00807-8

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