PHYLOGENETIC ASSOCIATION MAPPING

DNA methylation makes mutational history

A quantitative phylogenetic association mapping approach links genic mutational spectra to the evolution of DNA methylation in the Brassicaceae family of flowering plants. The method has wider applications and may usher in a new era in our understanding of species diversity.

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Fig. 1: CMT3-mediated evolution of gbM shapes the mutational spectrum of genes.

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Correspondence to Frank Johannes.

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Johannes, F. DNA methylation makes mutational history. Nat. Plants 5, 772–773 (2019). https://doi.org/10.1038/s41477-019-0491-z

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