Information and function of a genome are not only decorated with epigenetic marks in the linear DNA sequence but also in their non-random spatial organization in the nucleus. Recent research has revealed that three-dimensional (3D) chromatin organization is highly correlated with the functionality of the genome, contributing to many cellular processes. Driven by the improvements in chromatin conformation capture methods and visualization techniques, the past decade has been an exciting period for the study of plants’ 3D genome structures, and our knowledge in this area has been substantially advanced. This Review describes our current understanding of plant chromatin organization and positioning beyond the nucleosomal level, and discusses future directions.
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This work has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 757600). We apologize to our colleagues whose work was not included or discussed sufficiently in this manuscript due to space constraints.
The authors declare no competing interests.
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Doğan, E.S., Liu, C. Three-dimensional chromatin packing and positioning of plant genomes. Nature Plants 4, 521–529 (2018). https://doi.org/10.1038/s41477-018-0199-5
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