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Sometimes a rocker-switch motion

Plastids are integrated into the cellular metabolism by several metabolite and ion transporters. The first crystal structure of one of these transporters, a member of the plastid phosphate transporter family, unravels a rocker-switch transport mode and serves as lead structure for other plastidial and endomembrane system transporters.

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Fig. 1: Function and evolutionary relationships of plastidial phosphate translocators.


  1. Yoon, H. S., Hackett, J. D., Ciniglia, C., Pinto, G. & Bhattacharya, D. Mol. Biol. Evol. 21, 809–818 (2004).

    Article  CAS  PubMed  Google Scholar 

  2. Flügge, U. I. Annu. Rev. Plant Physiol. Plant Mol. Biol. 50, 27–45 (1999).

    Article  PubMed  Google Scholar 

  3. Lee, Y. et al. Nat. Plants (2017).

    Google Scholar 

  4. Flügge, U. I. Biochim. Biophys. Acta 815, 299–305 (1985).

    Article  Google Scholar 

  5. Flügge, U. I. J. Exp. Bot. 46, 1317–1323 (1995).

    Article  Google Scholar 

  6. Gross, A., Brückner, G., Heldt, H. W. & Flügge, U. I. Planta 180, 262–271 (1990).

    Article  CAS  PubMed  Google Scholar 

  7. Brooks, C. F. et al. Cell Host Microbe 7, 62–73 (2010).

    Article  CAS  PubMed  Google Scholar 

  8. Weber, A. P. M., Linka, M. & Bhattacharya, D. Eukaryot. Cell 5, 609–612 (2006).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Orellana, A., Moraga, C., Araya, M. & Moreno, A. J. Mol. Biol. 428, 3150–3165 (2016).

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Karsten Fischer or Andreas P. M. Weber.

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Fischer, K., Weber, A.P.M. Sometimes a rocker-switch motion. Nature Plants 3, 771–772 (2017).

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