New genomic maps reveal that R-loop structures formed upon hybridization of nascent RNA transcripts to the DNA template are a common characteristic of Arabidopsis chromatin that may have a broad impact on gene expression.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Chédin, F. Trends Genet. 32, 828–838 (2016).
Skourti-Stathaki, K. & Proudfoot, N. J. Genes Dev. 28, 1384–1396 (2014).
Aguilera, A. & Garcia-Muse, T. Mol. Cell 46, 115–124 (2012).
Hamperl, S. & Cimprich, K. A. DNA Rep. 19, 84–94 (2014).
Santos-Pereira, J. M. & Aguilera, A. Nat. Rev. Genet. 16, 583–597 (2015).
Xu, W. et al. Nat. Plants http://dx.doi.org/10.1038/s41477-017-0004-x (2017).
Ginno, P. A., Lott, P. L., Christensen, H. C., Korf, I. & Chédin, F. Mol. Cell 45, 814–825 (2012).
Sanz, L. A. et al. Mol. Cell 63, 167–178 (2016).
Wahba, L., Costantino, L., Tan, F. J., Zimmer, A. & Koshland, D. Genes Dev. 30, 1327–1338 (2016).
Huppert, J. L. Mol. Biosyst. 4, 686–691 (2008).
Wendte, J. M. & Pikaard, C. S. Biochim. Biophys. Acta 1860, 140–148 (2017).
Pikaard, C. S., Haag, J. R., Pontes, O. M., Blevins, T. & Cocklin, R. Cold Spring Harb. Symp. Quant. Biol. 77, 205–212 (2012).
Boque-Sastre, R. et al. Proc. Natl Acad. Sci. USA 112, 5785–5790 (2015).
Chan, Y. A. et al. PLoS Genet. 10, e1004288 (2014).
Whittaker, C. & Dean, C. Annu. Rev. Cell Dev. Biol. http://doi.org/cbp5 (2017).
Sun, Q., Csorba, T., Skourti-Stathaki, K., Proudfoot, N. J. & Dean, C. Science 340, 619–621 (2013).
Shafiq, S. et al. Mol. Plant 10, 821–833 (2017).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Chédin, F. Hybrids in the chromatin. Nature Plants 3, 692–693 (2017). https://doi.org/10.1038/s41477-017-0011-y
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41477-017-0011-y