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Drug-resistant cell lines in cancer

Nature Communications volume 15, Article number: 8253 (2024) Cite this article

Over the years, clinical landscape of patients with cancer has dramatically changed due to the development of new and refinement of existing therapies. However, while patients may initially respond favorably to treatment, the development of resistance remains a major limitation. To understand and identify approaches to overcome mechanism of resistance, the availability of suitable resistant cancer models is critical. This post from Nature Communications illustrates how drug-resistant cancer cell lines can be developed and discusses how they can be used to address the issue of cancer therapy resistance.

This poster is freely available online thanks to support from CancerTools.org.

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Authors and Affiliations

  1. Dr Petra Joh Research Institute, Komturstraße 3 A, 60528, Frankfurt am Main, Germany

    Jindrich Cinatl Jr & Martin Michaelis

  2. School of Biosciences, University of Kent, Canterbury, CT2 7NJ, UK

    Mark N. Wass & Martin Michaelis

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  1. Jindrich Cinatl Jr
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  2. Mark N. Wass
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  3. Martin Michaelis
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Correspondence to Martin Michaelis.

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Cinatl, J., Wass, M.N. & Michaelis, M. Drug-resistant cell lines in cancer. Nat Commun 15, 8253 (2024). https://doi.org/10.1038/s41467-024-52441-z

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  • DOI: https://doi.org/10.1038/s41467-024-52441-z

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