Fig. 4: Dose curve responses of the top drug hits. | Nature Communications

Fig. 4: Dose curve responses of the top drug hits.

From: Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

Fig. 4

Dose–response curves of the probability resembling the positive control by concentration for T11 (a) and T12 (b) organoids. Data points represent the mean and standard deviation of four technical replicates. Curves are fit using a constrained 4-parameter logistic using Graphpad Prism. The resulting curve fit parameters describing efficacy (top probability score) and potency (LogPR50 concentration) are summarized in the lower table.

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