Table 2 Metabolic markers of patients with diabetes at baseline (0 m) and 1, 3, 6, and 12 months after surgery in the gastric bypass surgery intervention study.

From: Hyocholic acid species as novel biomarkers for metabolic disorders

  Baseline (0 month) (n = 38) 1 month after (n = 38) 3 months after (n = 38) 6 months after (n = 38) 12 months after (n = 38)
n (M/F) 38 (18/20) 38 (18/20) 38 (18/20) 38 (18/20) 38 (18/20)
Age (year) 45 ± 13 50 ± 13
BMI (kg/m2) 32.21 ± 3.84 28.10 ± 3.53* 25.95 ± 3.21* 24.78 ± 2.91* 24.53 ± 2.71*
Waist (cm) 107.18 ± 12.52 95.89 ± 9.80* 89.89 ± 9.78* 86.63 ± 9.08* 86.08 ± 8.49*
Glu0 (mmol/L) 8.0 ± 2.5 6.8 ± 1.8* 5.9 ± 1.6* 5.5 ± 1.1* 5.7 ± 1.1*
Glu120 (mmol/L) 12.3 ± 4.0 7.5 ± 2.5* 7.4 ± 3.1* 6.9 ± 3.0* 6.8 ± 2.6*
Ins0 (mU/L) 25.49 ± 22.38 13.03 ± 10.25* 8.02 ± 5.00* 7.20 ± 4.29* 7.28 ± 4.18*
Ins120 (mU/L) 105.24 ± 79.12 20.91 ± 17.38* 23.81 ± 20.74* 31.77 ± 32.02* 24.17 ± 19.51*
TC (mmol/L) 7.7 ± 1.9 6.7 ± 1.2* 6.0 ± 1.2* 5.9 ± 0.6* 5.9 ± 1.2*
TG (mmol/L) 2.6 ± 3.1 1.5 ± 0.6* 1.2 ± 0.6* 1.1 ± 0.6* 1.0 ± 0.6*
HDL-c (mmol/L) 1.02 ± 0.16 0.96 ± 0.19 1.03 ± 0.19 1.16 ± 0.19* 1.26 ± 0.27*
LDL-c (mmol/L) 3.10 ± 0.91 3.15 ± 0.90 2.61 ± 0.61* 2.49 ± 0.74* 2.49 ± 0.63*
HbA1c (%) 7.7 ± 1.7 6.7 ± 1.1* 6.0 ± 1.0* 5.8 ± 0.8* 5.9 ± 1.0*
HOMA-IR 8.92 ± 7.65 4.16 ± 4.36* 2.13 ± 1.52* 1.79 ± 1.20* 1.86 ± 1.16*
  1. Values were presented as number or mean ± SD.
  2. *Two-sided Wilcoxon paired samples signed-rank p < 0.05 when compared with baseline (0 month).