Fig. 4: Performances of HCA species in the 10-year and 5-year longitudinal studies. | Nature Communications

Fig. 4: Performances of HCA species in the 10-year and 5-year longitudinal studies.

From: Hyocholic acid species as novel biomarkers for metabolic disorders

Fig. 4

In the 10-year longitudinal study, af total BAs, total and individual HCA species in the serum of matched all (n = 92), male (n = 20), and female (n = 72) individuals in future metabolically healthy (MH) (n = 46) and metabolically unhealthy (MU) (n = 46) groups. g ROC analyses of total and individual HCA species for the metabolic health longitudinal study. HCA species is the concentration summation of HCA, HDCA, GHCA, and GHDCA. In the 5-year longitudinal study, hm total BAs, total and individual HCA species in the serum of matched all (n = 174), male (n = 114), and female (n = 60) individuals in future MH (n = 87) and MU (n = 87) groups. n ROC analyses of total and individual HCA species for the metabolic health longitudinal study. HCA species is the concentration summation of HCA, HDCA, GHCA, GHDCA, THCA, and THDCA. Data are expressed as median with interquartile range (af, hm). *indicates statistical significance (p < 0.05) based on two-sided Mann–Whitney U test when comparing MH and MU.

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