Fig. 1: Catalytic properties of mAPE1 in exonucleolytic cleavage. | Nature Communications

Fig. 1: Catalytic properties of mAPE1 in exonucleolytic cleavage.

From: APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling

Fig. 1

a, b Substrate preference of mAPE1 in digesting ssDNA and dsDNA. Higher activity in digesting dsDNA substrates is observed for mAPE1. The activities of full-length and truncated mAPE1 display similar activity levels toward dsDNA, except mAPE1(Δ58) which shows a significant reduction in dsDNA degrading activity. a, b Source data are provided as a Source Data file.

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