Table 2 sOTUs identified via random forest as important for classifying 1,25(OH)2D, and/or the ratio of activation, ranked by importance score.

From: Vitamin D metabolites and the gut microbiome in older men

Taxa 1,25(OH)2Da Ratio of activationa Importance scoreb
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Ruminococcaceae, G-Oscillospira Negative Negative 0.0023, 0.0078
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Ruminococcaceae, G-Ruminococcus Positive N/A 0.004
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Lachnospiraceae, G-Blautia Negative Negative 0.0022, 0.0086
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Lachnospiraceae, G-Coprococcus, S-Catus Positive N/A 0.0026
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Lachnospiraceae, G-Blautia, S-Obeum Positive N/A 0.0028
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Ruminococcaceae, G-Anaerotruncus Negative N/A 0.0022
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Ruminococcaceae N/A Positive 0.0155
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Lachnospiraceae N/A Positive 0.0146
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Mogibacteriaceae, G-Mogibacterium N/A Positive 0.0131
P-Lentisphaerae, C-Lentisphaeria, O-Victivallales, F-Victivallaceae N/A Positive 0.0078
P-Firmicutes, C-Clostridia, O-Clostridiale N/A Positive 0.0149
P-Firmicutes, C-Clostridia, O-Clostridiales, F-Lachnospiraceae, G-Coprococcus N/A Positive 0.0233
  1. aDirection of associations between taxa identified by random forest and each vitamin D metabolite determined by Spearman rank correlation coefficients.
  2. bSignificance of correlation decided by Spearmanʼs p-value with BH-FDR correction.