Fig. 2: Somatic copy number alterations (SCNAs) in CMT genome profiles. | Nature Communications

Fig. 2: Somatic copy number alterations (SCNAs) in CMT genome profiles.

From: Cross-species oncogenic signatures of breast cancer in canine mammary tumors

Fig. 2

a A genome-wide heatmap of SCNAs is depicted, with red and blue representing chromosomal gains and losses, respectively. The cases are listed in order as in Fig. 1a. b Genome fractions with SCNAs were compared between 40 benign and 143 malignant CMTs, as well as between CMTs with or without TP53 mutations (n = 16 and 167, respectively). c Amplification and deletion peaks identified by GISTIC algorithms are shown across canine genomes with cancer-related genes belonging to the peaks shown. The significance was estimated by two-sided U tests.

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