a A genome-wide heatmap of SCNAs is depicted, with red and blue representing chromosomal gains and losses, respectively. The cases are listed in order as in Fig. 1a. b Genome fractions with SCNAs were compared between 40 benign and 143 malignant CMTs, as well as between CMTs with or without TP53 mutations (n = 16 and 167, respectively). c Amplification and deletion peaks identified by GISTIC algorithms are shown across canine genomes with cancer-related genes belonging to the peaks shown. The significance was estimated by two-sided U tests.