Fig. 7: APOBEC3A activity in a panel blood tumors. | Nature Communications

Fig. 7: APOBEC3A activity in a panel blood tumors.

From: Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots

Fig. 7

a Levels of edited DDOST558C>U were quantified using the ddPCR assay in a panel of patient blood tumor samples. For each sample, independent PCR reactions were performed to determine the level of edited DDOST558C>U. Error bar: S.D. (n ≥ 3) b, c Levels of A3A mRNA and edited DDOST558C>U were quantified by RT-qPCR and ddPCR respectively in the indicated patients’ blood tumor samples. For each sample, three or more independent PCR reactions were performed to determine the level of A3A mRNA or DDOST558C>U. Error bar: S.D. Edited DDOST558C>U level results showed in c were duplicated from the a of the corresponding patient samples. Source data are provided as a Source Data file.

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