Fig. 2: Histogram of number of qualifying variants per gene in European UKB cohort. | Nature Communications

Fig. 2: Histogram of number of qualifying variants per gene in European UKB cohort.

From: Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts

Fig. 2

a Number of qualifying coding variants per gene. Eleven genes with >500 variants were excluded from plot. The median of variants per gene is 34 (range [1:2833]). b Number of qualifying coding variants per coding nucleotide of each gene. Sixteen genes with values >0.2 were excluded from the plot. The median of variants per nucleotide is 0.027 (range [0.0001:0.991]). c Number of qualifying loss of function (LoF) variants per gene. Six genes with >50 variants were excluded from plot. The median of variants per gene is six (range [1:178]). d Number of qualifying LoF variants per coding nucleotide of each gene. Nine genes with values >0.05 were excluded from the plot. The median of variants per nucleotide is 0.005 (range [9.5 × 10−5:0.25]). Plots for all ancestries and HNP cohort can be found in Supplementary Fig. 1.

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