Table 2 Association of each APOE genotype in the neuropathologically confirmed group.

From: Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

APOECompared to APOE2/3Compared to APOE4/4
OR95% CIPOR95% CIP
2/20.340.12–0.950.040.0040.001–0.0146.0 × 10−19
2/3Ref.Ref.Ref.0.0120.006–0.0241.2 × 10−34
3/32.602.00–3.381.6 × 10−120.0320.017–0.0604.9 × 10−26
2/46.964.06–11.927.5 × 10−120.0860.039–0.1891.6 × 10−9
3/415.9211.85–21.381.4 × 10−700.1960.103–0.3758.4 × 10−7
4/481.0541.39–158.681.2 × 10−34Ref.Ref.Ref.
  1. Alzheimer’s dementia odds ratios (ORs), 95% confidence intervals (CIs), and P value (P) for each APOE genotype compared to the APOE2/3 or 4/4 genotype as a reference (Ref.) in the neuropathologically confirmed group were calculated under a logistic regression model.