Fig. 4: Low U1 AMO causes widespread alternative splicing changes in HeLa cells. | Nature Communications

Fig. 4: Low U1 AMO causes widespread alternative splicing changes in HeLa cells.

From: U1 snRNP regulates cancer cell migration and invasion in vitro

Fig. 4

a Summary of alternative splicing events as identified with JUM analysis. Each alternative splicing event happened in both low U1 AMO 12.5 and 62.5 pmole in HeLa cells. (A5’SS: alternative 5ʹ splice site; A3’SS: alternative 3ʹ splice site; CE: cassette exon; IR: intron retention; MXE: mutually exclusive exons) b Sashimi plots and genome browser view of each alternative splicing change in the low U1 AMO 12.5 and 62.5 pmole.

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