Fig. 4: Stable expression of STAND proteins in the SNc. | Nature Communications

Fig. 4: Stable expression of STAND proteins in the SNc.

From: An ultra-stable cytoplasmic antibody engineered for in vivo applications

Fig. 4

al Immunohistochemical analysis of the SNc 33 days after injection with AAV9/3-STAND-A36 (ac, gi) or AAV9/3-STAND-M4 (df, jla, d, g, j Anti-Flag antibody to detect scFv protein; b, e, h, k anti-tyrosine hydroxylase [TH] antibody used to detect dopaminergic neurons; c, f, i, l merged image of a and b, d and e, g and h, or j and k. gl Magnified images of the SNc region in ac or df. STAND proteins were stably expressed in the cytoplasm of dopaminergic neurons (arrows). Scale bars, 200 μm cf and 50 μm il.

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