Table 3 Comparison of biochemical recurrence (BCR) within 1 year.

From: Automated acquisition of explainable knowledge from unannotated histopathology images

 AUCaPseudo R-squared
Gleason score (pathologist)0.721 [95% CI 0.552–0.889]0.110 [p-value 0.030]
Ridge (automated)0.829 [95% CI 0.743–0.915]0.244 [p-value 0.0010]
Lasso (automated)0.810 [95% CI 0.700–0.921]0.207 [p-value 0.0026]
SVM (automated)0.845 [95% CI 0.761–0.928]0.260 [p-value 0.00069]
Ridge + Gleason score0.871 [95% CI 0.782–0.960]0.310 [p-value 0.00019]
Lasso + Gleason score0.884 [95% CI 0.782–0.985]0.294 [p-value 0.00029]
SVM + Gleason score0.882 [95% CI 0.803–0.962]0.319 [p-value 0.00015]
  1. BCR predictions at St. Marianna University Hospital (SMH) and Aichi Medical University Hospital (AMH) (external validation)
  2. The reported values are averages with 95% confidence interval. The bold values indicate the highest accuracies for lasso, ridge and support vector machine (SVM)
  3. aArea under the curve (AUC)