Fig. 9 | Nature Communications

Fig. 9

From: Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23

Fig. 9

Mice with necrotizing enterocolitis (NEC) show decreased production of pancreatic enzymes. ac Expression of IL-23p19 (a) and IL-22 (b) mRNA in the terminal ileum of control and animals with NEC (n = 8 mice/group). c Quantification of IL-22 in the serum of control and animals with NEC (n = 6–12 mice/group). d Representative immunostaining of pancreas of control mice and mice with NEC. Insets show higher magnification (n = 7–8 mice/group). Scale bars = 50 μm. e Quantification of fluorescence intensity in images shown in d (n = 7–8 mice/group). Data are shown as mean ± SEM, statistical analysis by nonparametric Mann–Whitney test. **p < 0.01 and ***p < 0.001. Source data are provided as a Source Data file

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