Fig. 6 | Nature Communications

Fig. 6

From: Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23

Fig. 6

Altered food absorption pathways in the jejunum of KSR23 mice. a Principal component analysis of RNASeq expression data from all biological replicates of WT and KSR23 jejunum (n = 5/group). b Plot of log 2 FC (log 2 fold change) vs. log 2 CPM (log 2 counts per million) of all detected transcripts. Points are colored according to expression status: non-significant genes (gray) and significant genes (698 genes; Q < 0.05; log 2 FC > 2 or log 2 FC < −2; red). c Z-scored heat map of all downregulated genes associated with the GO terms “protein digestion and absorption.” d ClueGo analysis of significantly downregulated genes shown enrichment of GO term group “very-low-density lipoprotein particle.” e Z-scored heat map of all downregulated genes associated with the GO group “very-low-density lipoprotein particle”

Back to article page