Fig. 1 | Nature Communications

Fig. 1

From: Reply to ‘Concerns about the feasibility of using “precision guided sterile males” to control insects’

Fig. 1

Model-predicted impact of releases of pgSIT eggs on Aedes aegypti mosquito population density with comparison to releases of Wolbachia-based incompatible insect technique (IIT), release of insects carrying a dominant lethal gene (RIDL), and female-specific RIDL (fsRIDL). Releases are carried out weekly over a 6-month period with release ratios (relative to wild adults) shown in the key. Model predictions were computed using 2000 realizations of the stochastic implementation of the MGDrivE simulation framework5 for a randomly mixing Ae. aegypti population of 10,000 adult females and model parameters described in Supplemental Table 10 of Kandul et al. 1 Previous results suggested that pgSIT releases outcompete those of other suppression technologies when pgSIT mating competitiveness is estimated from lab experiments for Drosophila melanogaster (purple). However, pgSIT and fsRIDL perform similarly well when mating competitiveness is estimated from field releases of RIDL strains of Aedes aegypti (green and red, respectively)

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