Fig. 6 | Nature Communications

Fig. 6

From: Targeting the HIV-infected brain to improve ischemic stroke outcome

Fig. 6

ART CPE score correlates with post-stroke treatment outcome. a Quantification of infarct size of non-infected mice treated with ART-7 or ART-11. Mice were administered with antiretroviral drugs as ART-7 or ART-11 mixture for 2 weeks. Then, ischemic stroke was induced and infarct volume was assessed 24 h post-stroke. b, c Mice were infected with EcoHIV as in Fig. 1, and ART-7 or ART-11 was introduced one week later for 2 weeks. Then, ischemic stroke was induced, and infarct volume was evaluated after 24 h (b) or 7 days (c). ART continued to be administered post-stroke; n = 7–11 mice per group, 2 independent experiments. Data presented as mean and SEM. Source data are provided as a Source Data file. *p < 0.05 or **p < 0.01; one-way ANOVA, followed by Tukey multiple comparison test

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