Fig. 2 | Nature Communications

Fig. 2

From: Structural basis for functional interactions in dimers of SLC26 transporters

Fig. 2

Interspin distances in the SLC26Dg dimer. a Primary PELDOR data of detergent-solubilized K353R1. bd Left panels: background-corrected PELDOR time traces for membrane-reconstituted K353R1, V367R1, and L385R1 (black traces), overlaid with the fit from Tikhonov regularization (green), and forward-calculated PELDOR time traces from BioEn spin-label rotamer refinement of the MD simulation model (magenta, dashed; θ = 10). Right panels: distance distributions obtained by Tikhonov regularization (green), overlaid with the distance distributions resulting from BioEn analysis of the MD simulation model (magenta, dashed). Original PELDOR data in Supplementary Fig. 2. e Cα-atom root mean squared distance (RMSD) values of the core, gate, TM13, and 14 relative to the monomer crystal structure as a function of MD time (1 μs)

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