Fig. 2 | Nature Communications

Fig. 2

From: Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening

Fig. 2

Fusions impact gene expression. a Frequency of a statistical association between a recurrent fusion (n > 2 cell lines) and differential gene expression. Examples of downregulated tumour suppressor genes (TSGs) and overexpressed oncogenes are displayed. b Frequency of co-occurrence of a gene fusion and overexpression of the 3′ gene for each fusion event. RSPO2, RSPO3, and NUTM1 are examples of overexpressed cancer driver genes involved in previously unreported gene fusions

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