Fig. 2 | Nature Communications

Fig. 2

From: Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Fig. 2

Reproducibility of independent in vitro drug combination datasets. a Comparison of the maximum drug concentration used in the AZ-DREAM, O’Neil et al.4 and ALMANAC datasets. b Synergy scores of identical drug combinations in AZ-DREAM and ALMANAC. Horizontal and vertical striped lines mark the threshold for synergistic and antagonistic, where positive and negative scores confirm synergy and antagonism, respectively. c Shows cell viability for each of the 38 overlapping experimental titration points that are identical in AZ-DREAM and ALMANAC across the nine drug combination experiments, significance calculated with test for association (Supplementary Fig. 3)

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