Fig. 1 | Nature Communications

Fig. 1

From: Muscle functions as a connective tissue and source of extracellular matrix in planarians

Fig. 1

The planarian matrisome includes proteins with highly conserved domain structures. a Domains present in both planarians and humans that define the matrisome24 were used, along with blastx hits to human matrisome proteins, to categorize the ~750 contigs as shown and define the planarian matrisome. Light colored lines indicate low confidence in ECM localization. SIP, signal peptide. b Phylogenetic relationship between planarians and other model organisms showing the ancient origin of basement membrane proteins and gain or loss of important ECM proteins. c Domain architectures, colored as in Fig. 1a, of core matrisome proteins which are conserved between planarians and humans. Domains in parentheses have indicated number of repeats. Numbers in square brackets indicate number of proteins in Schmidtea mediterranea (S. med) or Homo sapiens (H. sap) with indicated domain architecture. d Domain architectures found in the planarian core matrisome not found in humans

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