Fig. 1 | Nature Communications

Fig. 1

From: Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction

Fig. 1

Expression of mir-19a/miR-19b in the heart and cardiomyocytes. a qRT-PCR of miR-19a and miR-19b at 2 and 12 days postnatal mouse hearts. n = 3 mice. b In isolated adult cardiomyocytes and non-cardiomyocytes, qRT-PCR detection of the expression of miR-19a. n = 3 mice. c, d In mouse myocardial infarction (MI) model, qRT-PCR detection of the expression of miR-19a and miR-19b (c) at 3 days post-MI (n = 6 mice) and (d) at 2 weeks and 4 weeks post-MI. n = 3–6 mice. e In mouse transverse aortic constriction (TAC) induced cardiac hypertrophy model, qRT-PCR detection of the expression of miR-19a, miR-19b, and miR-21 at 3 days and 2 weeks post-TAC. Expression of miR-21 was considered as positive control. n = 2–3 mice. f In human heart disease samples, qRT-PCR detection of the expression of pri-mir19a in hearts with dilated cardiomyopathy (DCM) and coronary artery disease (CAD). The expression of ANF (encoded by Nppa) was considered as positive control. All panels, statistical significance was calculated using Student’s t-test and data are presented as means ± s.e.m. *p < 0.05, **p < 0.01 vs. control. Source data are provided as a Source Data file

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