Fig. 2 | Nature Communications

Fig. 2

From: A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease

Fig. 2

Gut microbiome alteration in NAFLD-cirrhosis. Comparison between non-NAFLD controls in blue (n = 51), NAFLD without advanced fibrosis in yellow (n = 17), and NAFLD-cirrhosis probands in pink (n = 25) with respect to a alpha-diversity using Faith’s Phylogenetic Diversity. Non-NAFLD controls have significantly higher alpha-diversity compared to probands with NAFLD without AF in yellow (p = 0.0163) and NAFLD-cirrhosis in pink (p = 0.0020). b Similar plot for beta-diversity using unweighted UniFrac distance metric. The beta-diversity among probands with NAFLD without AF in yellow was significantly lower than that among non-NAFLD controls in blue (p = 1.14E-18) and probands with NAFLD-cirrhosis in pink (p = 3.32E-15). The box plots show the quartiles and whiskers show the rest of the distribution (1.5 inter-quartile range) the center liner corresponds to the median. c Gut microbiome composition of non-NAFLD controls, NAFLD without AF and NALFD-cirrhosis probands shows differences at bacterial genus level. All p value were determined by two-sided Kruskal-Wallis test. *p value < 0.05. Source data are provided as a Source Data file