Fig. 3 | Nature Communications

Fig. 3

From: Simulations suggest a constrictive force is required for Gram-negative bacterial cell division

Fig. 3

Detailed effect of the constrictive force. The arrows between the zoomed-in views in the bottom two rows indicate the time sequence of events. a Without the force, the new strand tips were at some distance from the existing crosslink that was targeted for cleavage (highlighted in cyan). After the target crosslink was cleaved, new peptidoglycan (PG) was matched one-to-one with the existing template. b In the presence of a small force, the midcell was squeezed, pulling the new strand tips closer to the target crosslink (highlighted in cyan). After the target crosslink was cleaved, the new PG was still matched one-to-one with the default template. c In the presence of a large force, the new strand tips were pulled past the default target crosslink (highlighted in cyan), therefore skipping it, and an upstream crosslink (highlighted in yellow) became the new target. After the new target crosslink was cleaved, the new PG was no longer matched one-to-one with the template. Note that several such template-skipping events occurred along each complete hoop of new PG

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