Fig. 9 | Nature Communications

Fig. 9

From: Odor mixtures of opposing valence unveil inter-glomerular crosstalk in the Drosophila antennal lobe

Fig. 9

Circuit model for glomerulus-specific crosstalk in the fly AL. a Stimulation with the attractive odor ethyl acetate activates the attractant-responsive glomeruli DM1, DM2, DM3, and DM4, which results in behavioral attraction. b The repellent odor benzaldehyde is blended with the attractive odor ethyl acetate. Benzaldehyde activates the repellent-responsive glomeruli DL1 and DL5 which induce an inhibition of the attractant-responsive glomeruli via two different subsets of GABAergic LNs: DL1 is mediating the inhibition of glomeruli DM1 and DM4 via HB4-93-type LNs, while glomeruli DM3 and, to some extent, DM2 are inhibited by DL5 via NP3056-type LNs. This inhibitory crosstalk shifts the mixture representation towards the repellent odor and consequently leads to a reduced behavioral attraction

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