Fig. 1 | Nature Communications

Fig. 1

From: Patients with basal ganglia damage show preserved learning in an economic game

Fig. 1

Lesion reconstruction and task schematic. a Structural MRI slices illustrating the lesion overlap across the two patient groups. All BG lesions were shown overlaid on the left hemisphere for comparison purposes (4L; 2R). BG group mean lesion volume was 10.6 cm3. Maximal lesion overlap was in the putamen and encompassed the head and body of the caudate as well as the globus pallidus in some patients. OFC group mean lesion volume was 113.5 cm3. Maximal lesion overlap was in Brodmann’s areas 10, 11, 13, and 14, centered in the OFC and including portions of areas 12, 25, and 47 in some patients. b Subjects were presented with the information regarding their endowment, the endowment of the opponent, and the potential prize. In the particular payoff structure we used, the prize is worth 10 units, and the Strong (Weak) player is endowed with five (4) units at the beginning of each round. Subjects then inputted the decision (self-paced) by pressing a button mapped to the desired investment amount from the initial endowment. If the subject’s investment was strictly more than that of the opponent, the subject won the prize; otherwise, the subject lost the prize. In the event of a tie, both lost the prize. In either case, the subject kept the portion of the endowment not invested. In the non-strategic condition, participants were told to choose an investment that must exceed a randomly generated hurdle to win the prize, but were not told how the computer generated the random hurdle. The hurdle followed the same empirical frequency of decisions as in the strategic condition. The experiment consisted of 160 rounds of Patent Race game, alternating between the strategic and non-strategic conditions over 80 rounds, counterbalanced

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