Fig. 3 | Nature Communications

Fig. 3

From: Dynamics of individual molecular shuttles under mechanical force

Fig. 3

Shuttling dynamics, positional control and energy profiles. a Extension vs. time data for single molecular shuttles at different constant forces. b Zoom-in on the data presented in a at arbitrary time intervals, showing residence and transition times. An average of 400 shuttling events were recorded for each molecular shuttle (N = 24). c Extension histograms, fitted with two Gaussian curves (orange and green lines) affording a shuttling distance of Δx ~ 15 nm. d Energy profiles at each force, obtained directly from the relative populations depicted in (c). At force < f1/2 (8.1 pN, left column), the macrocycle occupies preferentially the fum station (green). At force ~f1/2 (8.5 pN, middle column), both stations present similar occupancies . At force > f1/2 (9.6 pN, right column), the macrocycle occupies preferentially the succ station (orange)

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