Table 2 In vivo neutralization results for monoclonal IgG antibodies raised against Dp5, Dp6, and Dp7

From: In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies

  Venom fractions
IgG ID Dp5 Dp6 Dp7
  0.5:1 0.75:1 1:1 2:1 3:1 4:1 0.5:1 0.75:1 1:1 2:1 3:1 4:1 6:1 2:1 3:1 4:1 6:1
360_01_B12     0/4 4/4 4/4       1/4     1/4  
360_01_C09     0/4 1/4 4/4       0/4     1/4  
361_01_F07 2/4 3/4 3/4 4/4 4/4 3/4       2/4     1/4  
361_01_G08 0/4 1/4 2/4 2/4 4/4 4/4       1/4     0/4  
362_01_A08   3/4 3/4 4/4 4/4 4/4    1/4 2/4 3/4 3/4     0/4  
362_01_D01   2/4 3/4 3/4 3/4 3/4    0/4 2/4 2/4 4/4     1/4  
363_01_F07   4/4 4/4 4/4 4/4 4/4 0/4 0/4 2/4 4/4 4/4 4/4     1/4  
363_01_G12             0/4 0/4     
364_01_A01               0/4 0/4* 0/4 0/4
364_01_A04       0/4       0/4    1/4 3/4  
364_01_B01                1/4* 1/4 1/4
364_01_C11                 1/4  
364_01_D03                0/4* 0/4 0/4
364_01_D04                0/4* 1/4 0/4
365_01_G06   4/4 3/4 4/4 4/4 4/4     0/4 0/4 3/4   0/4 3/4 4/4  
  1. Monoclonal IgGs were tested against individual venom fractions using i.c.v administration. Numbers indicate survival ratios at 24 h. * denotes that intravenous (i.v.) administration was used instead of i.c.v. administration. Ratios are provided as molar ratios between IgG:toxin.