Table 1 Optimization studies

From: Enantioselective radical conjugate additions driven by a photoactive intramolecular iminium-ion-based EDA complex

Entry Catalyst 3 Eox (3·+/3) (V)a 4 [%] Yield of 2b [%] ee of 2
1 3a +1.15 4a 58 79
2 3a +1.15 4b 0
3 3a +1.15 4c 0
4 3a +1.15 4d 82 80
5 3b +1.05 4d 16 86
6 3c +0.96 4d 0
7 3d +1.16 4d 79 81
8 3e +1.09 4d 74 88
  1. Reactions performed at 35 °C on a 0.1 mmol scale using 1.5 equiv. of 4 under illumination by a single high-power (HP) LED (λmax = 420 nm)
  2. aEox of the redox-active carbazole unit within catalysts 3ae, as measured by cyclic voltammetry vs. Ag/Ag+ in CH3CN
  3. bYield of isolated 2