Fig. 7 | Nature Communications

Fig. 7

From: Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation

Fig. 7

Expression of TFs and targets in 1182 breast cancer patient samples. a The Spearman’s correlation of expression levels of top 50 TFScore predicted transcription factors in Fig. 4b. We randomly picked 50 expressed transcription factors and calculated their correlation values as the background distribution. The Wilcoxon Rank Sum test P-value is shown. b The Spearman’s Correlation of expression levels of 102 genes up-regulated during cell transformation and consistently down-regulated upon 6 factor knockdowns in Fig. 5a. We randomly picked 102 expressed genes and calculated their correlation values as the background distribution. The Wilcoxon Rank Sum test P-value is shown. c Relative expression of top 50 TFScore predicted transcription factor in indicated breast cancer subtypes. The numbers of patient samples were shown in parentheses, and the Wilcoxon Rank Sum test P-values comparing different groups are shown. d Relative expression of 102 target genes in indicated breast cancer subtypes. The numbers of patient samples were shown in parentheses, and the Wilcoxon Rank Sum test P-values comparing different groups are shown

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