Fig. 3 | Nature Communications

Fig. 3

From: Diffusion markers of dendritic density and arborization in gray matter predict differences in intelligence

Fig. 3

Partial correlation analyses with data from sample S259 quantifying structure–function associations at the level of single brain regions. For each hemisphere, 180 cortical brain regions were defined based on the multi-modal parcellation scheme provided by the Human Connectome Project. NODDI coefficients and volume measures from homotopic brain regions were averaged across both hemispheres, resulting in 180 mean values. Structure–function associations between INVFCortex and intelligence (a) as well as ODICortex and intelligence (b) were analyzed by means of partial correlations with age, sex, and the remaining cortical brain properties as controlling variables. FDR correction using the Benjamini–Hochberg method was applied to account for a total of 180 comparisons. Partial correlation coefficients are depicted as gray bars arranged by magnitude from negative to positive. Due to space restrictions, a middle portion of 110 brain regions exhibiting no significant structure–function associations is spared out. Statistically significant partial correlation coefficients that survived a critical FDR threshold of q = 0.05 (see Methods) are highlighted in either red or yellow. The yellow color marks significant partial correlation coefficients that are exhibited by brain regions from the P-FIT model of intelligence. Following this color scheme, respective brain regions are marked in either red or yellow on a cortical surface. INVFCortex = intra-neurite volume fraction representing neurite density in the cortex, ODICortex = orientation dispersion index of neurites in the cortex

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