Table 1 Catalyst screening and reaction condition optimization with molecular catalysts

From: Synthesis of a molecularly defined single-active site heterogeneous catalyst for selective oxidation of N-heterocycles

Entry Catalyst Conversion (%)a Selectivity (%)a
1 0 Trace Trace
2 Cat-1 86 44
3 Cat-2 >99 Trace
4 Cat-3 29 43
5 Cat-4 48 40
6 Cat-5 100 49
7 Cat-6 100 71
8 Cat-7 91 70
9 Cat-8 4 56
  1. Reaction conditions: 0.5 mmol catalyst, 0.5 mmol 1,2,3,4-tetrahydroquinoline, 1 atm O2, solvents (1 mL H2O + 1 mL CH3OH), 120 °C (oven temperature), 300 rps, 24 h
  2. a The conversion and selectivity were determined by GC-FID with the external standard method