Fig. 3 | Nature Communications

Fig. 3

From: Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

Fig. 3

Genomic distribution of eccDNA breakpoints. Distribution of detected chromosomal breakpoints across the human genome with read support for circular DNA, in sizes of ≤25 kb (total 147,186) and b >25 kb apart (total 1,014) in muscle (T1–T16, n = 16) and leukocyte (B1–B16, n = 16) samples. EccDNA detected once, black lines; eccDNA detected repeatedly in several individuals with ≥90% overlap, circles