Table 1 Consensus changes in DN-2 and DN-1 after serial passage in Vero cells

From: A systematic approach to the development of a safe live attenuated Zika vaccine

Virus Position Passage number Gene Mutation
1 2 3 4 5 6 7
DN-2 948 G G G G G G G M
2904 A A A T T T T NS1 T → S
DN-1 2449 T T T C C C C E L → S
2925a A A A A G G G NS1 K → E
4197 C C C T T T T NS2A Silent
8772 G G G A A A A NS5 E → K